Professional profile

Dr. José Antonio Encinar is an Associate Professor (Profesor Titular de Universidad) of Biochemistry and Molecular Biology in the Department of Biochemistry and Molecular Biology at Miguel Hernández University of Elche. He obtained his Ph.D. in Biochemistry-Neuroscience in 1998 from the Instituto de Neurociencias de Alicante, where he received the Extraordinary Doctoral Award in the Neurosciences program.Dr. José Antonio Encinar He completed two postdoctoral stays: one in Paris at the Institut de Biologie Physico-Chimique under the supervision of Prof. Philippe Devaux, and another in Heidelberg at the European Molecular Biology Laboratory (EMBL) with Prof. Luis Serrano.

Dr. Encinar’s current research focuses on the use of computational approaches to develop compounds that modulate the activity of proteins with biomedical relevance (cancer, obesity, diabetes). His work involves molecular modeling, docking, and molecular dynamics to perform high-throughput screening of chemical libraries and identify candidate compounds to modulate protein activity, which are subsequently evaluated experimentally. To date, he has co-authored 92 primary and review articles. He currently conducts his research at the Institute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE). His most recent research productivity assessment (quinto sexenio) was granted on June 9, 2024, for the period 2018-2023.

He is co-inventor of patent WO2022152800A1 on the use of a compound as an inhibitor of the interaction between βTrCP and NRF2 proteins, which is licensed to the company Servatrix S.L. This compound was initially identified by Dr. Encinar using computational methods. As a result of other collaborative projects, he is also listed as co-inventor on two additional patent applications: one for a competitive inhibitor of the PTPRK phosphatase, and another for an inhibitor of the CDK4/cyclin D1 enzyme. Furthermore, Prof. Encinar originally proposed compound RN, based on computational studies, as a competitive inhibitor of the PDE7 enzyme.

A full list of publications is available at: https://shaker.umh.es/publications/

Bibliometrics:
- Total citations: 3609 (December 2025), h-index: 35 (Google Scholar): https://scholar.google.com/citations?user=jTdMuycAAAAJ
- Total citations: 2599 (December 2025), h-index: 30 (Scopus): https://www.scopus.com/authid/detail.uri?authorId=35268584800

As a lecturer, Dr. Encinar has participated in a wide range of teaching activities in the Bachelor’s programs in Biochemistry, Biotechnology, and Food Science and Technology at the (Higher Polytechnic School of Orihuela (Miguel Hernández University of Elche).


Indicators of scientific productivity

Contact address

Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE).
Av. de la Universidad. Edif. Torregaitan. E-03202. Elche. Alicante. Spain. Despacho 2,08.
Despacho 45 (Orihuela).
Telephone number: + 34 96-665 8453
E-mail: jant.encinar@umh.es

Academic background

Professional background

Teaching activities

Biography

Born in Cardeñosa (Ávila - Spain) in 1968.