Estructuras de alta resolución de canales iónicos de potasio.

Ejemplo de proteína de membrana con estructura cuaternaria: Canal de potasio KcsA (secuencia 19-123) Quimera recombinante de los canales de potasio KV1.2-KV2.1
Canal de potasio KcsA completo de Streptomyces lividans embebido en una bicapa lipídica.
Canal de potasio MthK (secuencia 19-98).
Canal de potasio KcsA (secuencia 19-123)


Algunas estructuras de canales iónicos de potasio disponibles en el PDB.

  1. 1BL8: POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS.
    PubMed: 9525859
  2. 1F6G: POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD.
    PubMed 11158168
  3. 1J95: KCSA potassium channel with TBA (tetrabutylammonium) and potassium.
    PubMed 11395760
  4. 1JVM: KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND RUBIDIUM.
    PubMed 11689935
  5. 1K4C: Potassium Channel KcsA-Fab complex in high concentration of K+.
    PubMed 11689936
  6. 1K4D: Potassium Channel KcsA-Fab complex in low concentration of K+.
    PubMed 11689936
  7. 1LNQ: CRYSTAL STRUCTURE OF Methanobacterium thermoautotrophicum (MTHK) AT 3.3 A.
    PubMed 12037559
  8. 1ORS: X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab.
    PubMed 12721618
  9. 1R3I: Potassium channel KcsA-Fab complex in Rb+.
    PubMed 14583193
  10. 1R3J: Potassium channel KcsA-Fab complex in high concentration of Tl+.
    PubMed 14583193
  11. 1R3K: Potassium channel KcsA-Fab complex in low concentration of Tl+.
    PubMed 14583193
  12. 1R3L: Potassium channel KcsA-Fab complex in Cs+.
    PubMed 14583193
  13. 1S5H: Potassium Channel Kcsa-Fab Complex T75C mutant in K+.
    PubMed 15099749
  14. 1ZWI: Structure of mutant KcsA-E71A potassium channel.
    PubMed 16532009
  15. 2A79: Mammalian Shaker Kv1.2 potassium channel-beta subunit complex.
    PubMed 16002581
  16. 2ATK: Structure of a mutant KcsA-E71A K+ channel.
    PubMed 16532009
  17. 2H8P: Structure of a K+ channel with an amide to ester substitution in the selectivity filter.
    PubMed 16939283
  18. 2HFE: Rb+ complex of a K+ channel with an amide to ester substitution in the selectivity filter.
    PubMed 16939283
  19. 2HG5: Cs+ complex of a K+ channel with an amide to ester substitution in the selectivity filter.
    PubMed 16939283
  20. 2IH1: Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation.
    PubMed 17095703
  21. 2IH3: Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation.
    PubMed 17095703
  22. 2ITC: Potassium Channel KcsA-Fab complex in Sodium Chloride.
    PubMed 17472437
  23. 2ITD: Potassium Channel KcsA-Fab complex in Barium Chloride.
    PubMed 17472437
  24. 2NLJ: Potassium Channel KcsA(M96V)-Fab complex in KCl.
    PubMed 17472437
  25. 2P7T: Crystal Structure of KcsA(E71T) mutant (Perozo's group).
    PubMed 17922012
  26. 2QKS: Crystal structure of a Kir3.1-prokaryotic Kir channel chimera.
    PubMed 17703190
  27. 2R9R: Shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle chimera channel) in association with beta subunit.
    PubMed 18004376
  28. 3EFF: The Crystal Structure of Full-Length KcsA in its Closed Conformation.
    PubMed 19346472
  29. 3F5W: KcsA Potassium channel in the open-inactivated state with 32 A opening at T112.
    DOI: 10.1038/nature09153
  30. 3F7V: KcsA Potassium channel in the open-inactivated state with 23 A opening at T112.
    DOI: 10.1038/nature09153
  31. 3F7Y: KcsA Potassium channel in the open-inactivated state with 32 A opening at T112.
    DOI: 10.1038/nature09153
  32. 3FB5: KcsA potassium channel in the partially open state with 14.5 A opening at T112.
    DOI: １０．１０３８／nature０９１５３
  33. 3FB6: KcsA Potassium channel in the partially open state with 16 A opening at T112.
    DOI: 10.1038/nature09153
  34. 3FB8: KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion.
    PubMed 20613845
  35. 3HPL: KcsA E71H-F103A mutant in the closed state.
    PubMed 20613845
  36. 3JYC: Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 Angstrom resolution.
    PubMed 20019282
  37. 3LNM: F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel.
    PubMed 20360102
  38. 3LUT: A Structural Model for the Full-length Shaker Potassium Channel Kv1.2.
    PubMed 20534430